ErbB-3 Receptor

A cell surface protein-tyrosine kinase receptor that is specific for NEUREGULINS. It has extensive homology to and can heterodimerize with the EGF RECEPTOR and the ERBB-2 RECEPTOR. Overexpression of the erbB-3 receptor is associated with TUMORIGENESIS.

Also Known As:

Receptor, ErbB-3; Proto-Oncogene Protein c-erbB-3; Proto-Oncogene Proteins erbB-3; Proto-oncogene-like Protein c-ErbB-2; Tyrosine Kinase-type Cell Surface Receptor HER3; HER 3 Proto Oncogene Protein; Protein c-ErbB-2, Proto-oncogene-like; Proto Oncogene Protein c erbB 3; Proto Oncogene Protein erbB 3; Proto Oncogene Proteins erbB 3; Proto oncogene like Protein c ErbB 2; Proto-Oncogene Protein, HER-3; Receptor, ErbB 3; Tyrosine Kinase type Cell Surface Receptor HER3; c erbB 3 Protein; c-ErbB-2, Proto-oncogene-like Protein; c-erbB-3, Proto-Oncogene Protein; erbB 3 Protein; erbB-3, Proto-Oncogene Protein; erbB-3, Proto-Oncogene Proteins; HER-3 Proto-Oncogene Protein; Proto-Oncogene Protein erbB-3; c-erbB-3 Protein; erbB-3 Protein

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Transferases: 6589
    - Phosphotransferases: 42769
      - Phosphotransferases (Alcohol Group Acceptor)
        Protein Kinases: 9677
        Protein-Tyrosine Kinases: 7697
        Receptor Protein-Tyrosine Kinases: 5999
        ErbB Receptors: 27986
        ErbB-3 Receptor: 16
Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Membrane Proteins: 10078
    - Cell Surface Receptors: 2125
      - Receptor Protein-Tyrosine Kinases: 5999
        ErbB Receptors: 27986
        ErbB-3 Receptor: 16
      - Peptide Receptors: 1159
        Growth Factor Receptors: 2663
        ErbB Receptors: 27986
        ErbB-3 Receptor: 16
  - Intracellular Signaling Peptides and Proteins: 32
    - Protein-Tyrosine Kinases: 7697
      - Receptor Protein-Tyrosine Kinases: 5999
        ErbB Receptors: 27986
        ErbB-3 Receptor: 16
  - Neoplasm Proteins: 2
    - Oncogene Proteins: 7793
      - Proto-Oncogene Proteins: 7
        ErbB-3 Receptor: 16
Biological Factors: 2472
- Biomarkers: 240291
  - Tumor Biomarkers: 15272
    - ErbB-3 Receptor: 16

S Spaventi Selected Research

S Spaventi Research Topics

Disease

Drug/Important Bio-Agent (IBA)